Evolve the Insanity symptom, and Spallin should be elected instead of the Vice President. After a few months you may see a popup stating "USA president taken ill", which is required for the achievement. Evolve your disease and make it lethal (no more than 10%). Evolve Drug Resistance 1 and 2 and any transmissions and non-lethal abilities, then infect the world until you reach the USA. Some luck is required to earn these achievements.
Easy "Chinese Nuclear Retaliation" and "Russian Nuclear Retaliation" achievements It will be difficult to win afterwards because research to find the cure will be very fast. Unlock "Blindness", and "Neuro-Enhancement 1, 2, and 3" to get the "Blind Genius" achievement. Gen-Sys must be researching on apes to cure the disease.
"Transcendence" is in the top left path of the symptoms list. Infect the remaining living population and unlock the "Transcendence" symptom to get the "Assuming Direct Control" achievement. Easy "Assuming Direct Control" achievement
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